![]() ![]() The availability of new components has led to a diversity in instrumentation new understanding of image formation by rigorous theory has led to new designs and, consequently, novel applications have resulted in notable progress. Recent advances in hardware and design have dramatically changed both instrumentation and availability over the past few years. 6 These advances have provided several variants to speed up data acquisition and enable new capabilities compared to the basic configuration of a broadband globar source, interferometer, and array detector-equipped microscope. 1, 2 Instrumentation had been largely similar to this initial setup for almost two decades with several innovations such as rapid scan imaging, 3, 4 time-resolved imaging, 5 faster detectors, and linear array systems. Modern IR spectroscopic imaging can be traced back nearly 25 years, with the coupling of an IR microscope to an array detector and an interferometer. The combination of vibrational mid-infrared (IR) spectroscopy and microscopy is especially attractive since the fundamental vibrational modes of samples are coincident with optical frequencies, thereby absorbing a large fraction of incident light and providing a strong signal. ![]() Optical chemical imaging seeks to nondestructively acquire spatially resolved chemical information without the use of labels or probes. ![]()
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